Acetaminophen Induced Hepatotoxicity: a Comprehensive Update Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function, Mechanism of acetaminophen induced hepatotoxicity. High dose of Download Scientific Diagram Tylenol and glutathione, actually explainedhere's the bullet points: * Lots of concern raised on social media re: glutathione depletion and acetaminophen use * Glutathione is used in the metabolism of acetaminophen and Acetaminophen metabolism