Do Vape Pens Get You High? Exploring the Effects and Potency The dangers of vaping Baylor College of Medicine Blog Network Teenagers and their parents should know about the effects of vaping nicotine during adolescence. Most vapes have very high levels of nicotine, a chemical that literally rewires your brain and gets you Vaping is banned in our schools. Did you know: Most vapes contain high levels of nicotine (often without the person knowing). The nicotine in one e cigarette can equal to 50 cigarettes High nicotine e cigarettes dominate the market, with sales increasing 15 fold in five years