Can you donate blood if you smoke? Smoking or Vaping Cannabis and Cardiovascular Function: Is 9Tetrahydrocannabinol the Main Culprit? Journal of the American Heart Association Yes, you can donate blood if you smoke or consume cannabis. The recipient of the blood will not get high, another common MYTH. All donors go through the same health We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating If you use cannabis, do it safely Harvard Health